Chlorotriisopropylsilane

Catalog Number	ACM13154240-6
CAS Number	13154-24-0
Structure
Synonyms	Triisopropylsilyl chloride
Molecular Weight	192.81 g/mol
Molecular Formula	C9H21ClSi
Boiling Point	198 °C(739 mmHg)
Flash Point	64 °C
Purity	0.97
Density	0.901 g/mL
Application	Chlorotriisopropylsilane serves as a versatile silylating agent widely used in organic synthesis particularly valued for its role as a protective group for hydroxyl functions in complex molecules This compound is used to selectively protect and deprotect hydroxyl groups especially in polyfunctional hydroxyl compounds making it crucial in the synthesis of nucleosides nucleotides and carbohydrates The silylation reaction involving Chlorotriisopropylsilane is typically carried out in a slight excess of imidazole solution offering a unique balance of acid and base hydrolytic stability superior to similar protective agents Beyond its application in hydroxyl protection it acts as an important agent in the formation of silyl ynol ethers and supports various reactions involving pyrroles indoles and other heterocycles Additionally it is employed in the manufacture of organosilicon materials and acts as a blocking agent in silicone oil and rubber production enhancing the physical and mechanical properties of composites This reagent is thus integral to numerous chemical and pharmaceutical processes including the production of aminosilane and methacryloxysilane rubber processing and the preparation of antifungal and deodorant finishes with special functional properties
Storage	Moisture Sensitive
HS Code	Hazardous for shipping
MDL Number	MFCD00009656
Packaging	10 g
Refractive Index	1.452

Custom Reviews

November 01, 2024

Essential Silylation in Organic Synthesis

I've found Chlorotriisopropylsilane from Alfa Chemistry indispensable in my lab for hydroxyl protection. Its efficiency in DMF, alongside imidazole, is unmatched in nucleotide synthesis, ensuring reliable and stable results. Highly recommended for secure blocking needs.

※  Please kindly noted that this product is for research use only.

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