T-Butyldimethylchlorosilane, 3M In Tetrahydrofuran

Catalog Number	ACM18162486-12
CAS Number	18162-48-6
Structure
Molecular Weight	150.72 g/mol
Molecular Formula	C6H15ClSi
Application	T-Butyldimethylchlorosilane 3M in Tetrahydrofuran serves as a versatile protecting agent in organic synthesis Its primary function is to safeguard hydroxyl groups making it invaluable in areas like prostaglandin synthesis and as an auxiliary material for hypolipaemic drugs including lovastatin and simvastatin Additionally it plays a crucial role in preparing isoxazolines N-oxides from alpha-bromonitroalkanes and acts as a reliable protecting reagent for amines amides and alcohols Its application extends to the synthesis of ribonucleosides and as an oxidant and decyanide agent T-Butyldimethylchlorosilane is also notable for its efficiency in anion trapping demonstrated by its use in trapping lithio α-phenylthiocyclopropane anions and being integral in the synthesis of silyl stannanes The compound's utility spans the preparation of di-TBDMS-thiophene and facilitating reactions that produce cis-silyl stannylalkenes confirming its broad scope in diverse synthetic applications
Packaging	10 g; 100 g;

Custom Reviews

November 24, 2024

Outstanding Reagent for Protecting Hydroxyl Groups

Using Alfa Chemistry's T-Butyldimethylchlorosilane in our lab greatly enhanced our synthesis processes. It efficiently protected hydroxyl groups, crucial in prostaglandin synthesis. A reliable choice for complex organic synthesis tasks.

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