Tert-Butyldimethylchlorosilane

Catalog Number	ACM18162486-4
CAS Number	18162-48-6
Structure
Synonyms	tert-Butylchlorodimethylsilane tert-Butyldimethylsilyl chloride
Molecular Weight	150.73 g/mol
Molecular Formula	C6H15ClSi
Purity	0.97
Application	Tert-butyldimethylchlorosilane is a versatile organosilicon compound used as a protecting reagent for alcohols, amines, amides, and various carboxylic acids in organic synthesis. It is commonly applied in the synthesis of prostaglandins and as an auxiliary material for hypolipaemics like lovastatin and simvastatin. Additionally, it plays a crucial role in the preparation of isoxazolines N-oxides and is a valuable anion trapping reagent. Moreover, it is widely used as a protective group for hydroxyl in ribonucleoside synthesis and as an oxidant and decyanide. TBDMSCl is also utilized in trapping tin anions to prepare silyl stannanes, which can be used in the synthesis of cis-silyl stannylalkenes.
Storage	Moisture Sensitive. Ambient temperatures.

Custom Reviews

2024-8-30

Protecting Group Reagent for Organic Synthesis

As a chemist conducting research in organic synthesis, I have found tert-Butyldimethylchlorosilane from Alfa Chemistry to be an essential tool in my lab. This versatile protecting reagent has helped me safeguard hydroxyl groups in various compounds, aiding in the synthesis of prostaglandins and other important molecules. Its efficiency as an anion trapping reagent has also proven invaluable in my experiments, allowing me to isolate desired products with excellent yields. Overall, I highly recommend this product for researchers in need of a reliable protective agent in their chemical reactions.

※  Please kindly noted that this product is for research use only.

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