2024-8-2
Protective Agent for Hydroxyl Groups in Drug Synthesis
I recently used tert-Butyldimethylsilyl chloride from Alfa Chemistry in my research and found it to be a versatile protecting reagent for hydroxyl groups in drug synthesis. The sterically hindered organosilicon compound was easy to use and provided excellent protection for alcohols, amines, and amides. In my experiments, I was able to efficiently synthesize original drugs and create isoxazolines N-oxides with high yields. Overall, tert-Butyldimethylsilyl chloride proved to be a crucial component in my research and I highly recommend it for any scientist working in drug synthesis.
