Tert-Butyldiphenylchlorosilane, 97% 10G

Catalog Number	ACM58479611-4
CAS Number	58479-61-1
Structure
Synonyms	Tert-Butyldiphenylsilyl Chloride
Molecular Formula	C16H19ClSi
Boiling Point	90 °C(0.01 mmHg)
Flash Point	112 °C
Density	1.057 g/mL
Application	Tert-Butyldiphenylchlorosilane 97% 10G serves as a versatile silylating reagent specifically designed to protect primary and secondary alcohols by converting them into their corresponding TBDPS ethers The reagent efficiently transforms primary alcohols such as benzyl alcohol in DMF into silyl ethers with high yields within a short reaction time when combined with ammonium nitrate or perchlorate While less effective with silver nitrate it demonstrates its utility in the synthesis of ring-opened silyl ether carbonyl compounds from hemiacetals highlighting its significant role in addressing steric hindrance challenges Furthermore tert-Butyldiphenylchlorosilane is pivotal in organic synthesis and pharmaceutical manufacturing contributing to the development of compounds for treating circulatory disorders angina and stroke It is also instrumental in preparing intermediates for mono-O-protected pyrimidine acyclic nucleosides
Storage	Moisture Sensitive
HS Code	Hazardous for shipping
MDL Number	MFCD00000497
Refractive Index	1.568