Tert-Butyldiphenylchlorosilane

Catalog Number	ACM58479611-3
CAS Number	58479-61-1
Structure
Synonyms	tert-Butylchlorodiphenylsilane tert-Butyldiphenylsilyl chloride
Molecular Weight	274.87 g/mol
Molecular Formula	C16H19ClSi
Purity	0.97
Application	Tert-Butyldiphenylchlorosilane, also known as Tert-Butylchlorodiphenylsilane, is a versatile silylating agent used for derivatization of alcohols, ketones, carboxylic acids, amines, amides and mercaptanes into functional groups in various sterical environments. It is commonly utilized to protect primary and secondary alcohols as their TBDPS ethers, with the ability to selectively convert hemiacetals into ring-opened silyl ether carbonyl compounds. This compound serves as a crucial raw material and precursor in organic synthesis and pharmaceuticals, as well as in the synthesis of interphenylene phenyloxazoles for circulatory disorder treatment. Additionally, it plays a vital role in the preparation of key intermediates for the synthesis of mono-O-protected pyrimidine acyclic nucleosides.
Storage	Moisture Sensitive. Store under Nitrogen. Ambient temperatures.

Custom Reviews

2024-8-30

Protecting alcohols and creating silyl ethers has never been easier with Alfa Chemistry's Tert-Butyldiphenylchlorosilane.

As a silylating reagent, this product is essential for research in organic synthesis and pharmaceuticals. I have personally used it to successfully convert primary alcohols into functional groups within just 15 minutes, thanks to its excellent yields and unique properties. Additionally, the reagent's role in the synthesis of interphenylene phenyloxazoles showcases its versatility in various applications in the field of science and industry. Highly recommended for any researcher looking for reliable silylating agents.

※  Please kindly noted that this product is for research use only.

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