Triisopropylsilylchloride

Catalog Number	ACM13154240-5
CAS Number	13154-24-0
Structure
Molecular Weight	192.8 g/mol
Molecular Formula	C9H21ClSi
Boiling Point	199.1 °C(760 mmHg)
Flash Point	62.8 °C
Purity	0.99
Density	0.855 g/mL
Application	Triisopropylsilyl chloride serves as a versatile organosilicon protective agent primarily employed for the selective protection of hydroxyl groups in polyfunctional compounds during synthetic processes It plays a crucial role in the synthesis of nucleosides nucleotides and carbohydrates providing an efficient method for hydroxyl protection The silylation reaction using Triisopropylsilyl chloride takes place in the presence of a slight excess of imidazole solution offering intermediate acidic hydrolytic stability and superior alkaline hydrolytic stability compared to other silylating agents Additionally it acts as a catalyst in various chemical reactions including the preparation of (silyloxy)cyclobutene derivatives and the addition of diethylzinc to N-diphenylphosphinoyl imines Its utility extends to the prevention of chelation in Grignard reactions the protection of terminal alkynes pyrroles indoles and other heterocycles and the formation of functional silanes Furthermore Triisopropylsilyl chloride is instrumental in the production of antifungal and deodorant finishes due to its bactericidal and antistatic properties and it enhances the physical and mechanical properties of composites used in rubber processing