Trimethylbromosilane

Catalog Number	ACM2857978-1
CAS Number	2857-97-8
Structure
Synonyms	BROMOTRIMETHYLSILANE
Molecular Weight	153.09 g/mol
Molecular Formula	C3H9BrSi
Boiling Point	80
Melting Point	-44°C
Flash Point	-3°C
Purity	97%
Density	1.1725 g/mL
Application	Trimethylbromosilane is a versatile reagent that serves multiple purposes in chemical synthesis It is particularly effective as a selective agent for the protection or deprotection of functional groups Its mild nature makes it ideal for the cleavage of compounds like lactones epoxides acetals phosphonate esters and certain ethers Additionally Trimethylbromosilane is a powerful silylating agent used in the formation of silyl enol ethers and functions as a brominating agent It can also react with amines to form stable adducts that subsequently react with ketones to produce enamines under gentle conditions In pharmaceutical synthesis it plays a crucial role such as in the preparation of Adefovir intermediates Moreover Trimethylbromosilane especially when used with Cl3 efficiently catalyzes the direct allylation of various alcohols with allyltrimethylsilane
Storage	Moisture Sensitive
Chemical Formula	C3H9BrSi
EC Number	220-672-0
HS Code	Hazardous for shipping
MDL Number	MFCD00000048
Packaging	10 g; 100 g;
Refractive Index	1.422

Custom Reviews

November 29, 2024

Essential Reagent for Synthetic Chemistry

I've been using Alfa Chemistry's Trimethylbromosilane in my research to deprotect functional groups selectively. It's a powerful silylating agent, effective for forming silyl enol ethers and cleaving acetals. Reliable and efficient!

※ Please kindly noted that this product is for research use only.