1-Bromovinyltrimethylsilane

Catalog Number	ACM13683415-1
CAS Number	13683-41-5
Structure
Synonyms	(1-Bromoethenyl)(Trimethyl)Silane[(E)-2-bromoethenyl](trimethyl)silane(1-Bromoethynl)trimethylsilane
Molecular Weight	179.13 g/mol
Molecular Formula	C5H11BrSi
Boiling Point	124.9 °C(760 mmHg)
Flash Point	22.2 °C
Density	1.156 g/mL
Appearance	Straw Liquid
Application	1-Bromovinyltrimethylsilane serves as a versatile precursor in various chemical reactions particularly those involving substitution processes facilitated by palladium complexes It reacts with numerous nucleophiles allowing for the replacement of its bromine atom with diverse groups such as phenylthio vinyl and aryl yielding valuable products While these transformations generally provide reasonable yields they can sometimes lead to mixtures of regioisomers due to a lack of regiospecificity Two proposed mechanisms for these reactions include an elimination step forming trimethylsilylacetylene which subsequently undergoes catalytic addition at different positions and the formation of a pentacoordinated palladium intermediate that results in isomeric products Additionally when coupled with organozinc bromides in the presence of tetrakis(triphenylphosphine)palladium(0) 1-bromovinyltrimethylsilane exhibits its utility in generating a wide array of valuable synthetic intermediates
Packaging	10 g; 100 g;

Custom Reviews

November 28, 2024

Effective Partner in Organic Synthesis

Using 1-Bromovinyltrimethylsilane from Alfa Chemistry in our lab's coupling reactions with palladium successfully yielded diverse aryl groups, enhancing our research outcomes. The product's versatility, despite regiospecific challenges, was invaluable.

※  Please kindly noted that this product is for research use only.

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