(3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one

Catalog Number	ACM32384659
CAS Number	32384-65-9
Structure
Synonyms	D-Gluconic Acid, 2,3,4,6-Tetrakis-O-(Trimethylsilyl)-, Δ-Lactone 2,3,4,6, Tetrakis-O-(Trimethylsilyl)-D-Lactone, 2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Glucolactone D-2,3,4,6-Tetrakis-O-(Trimethylsilyl)-Gluconic Acid Delta-Lactone (3R,4S,5R,6R)-3,4,5-Tris((Trimethylsilyl)Oxy)-6-(((Trimethylsilyl)Oxy)Methyl)Tetrahydropyran-2-One (3R,4S,5R,6R)-3,4,5-Tris(Trimethylsilyloxy)-6-((Trimethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One (3R,4S,5R,6R)-3,4,5-Tris(Trimethylsilyloxy)-6-((Trimethylsilyloxy)Methyl)-Tetrahydropyran-2-One
Molecular Weight	466.868 g/mol
Molecular Formula	C18H42O6Si4
Application	The product (3R4S5R6R)-345-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one is designed to serve as a significant intermediate in the synthesis of antidiabetic agents specifically sodium glucose co-transporter 2 (SGLT2) inhibitors These inhibitors such as Dapagliflozin Empagliflozin and Canagliflozin are crucial for managing type 2 diabetes by regulating glucose reabsorption in the kidneys The product facilitates the creation of trans-cyclohexane-bearing C-glucose derivatives essential in the pharmacological design and development of these SGLT2 inhibitors Its role as a versatile reagent and key raw material underscores its importance in the pharmaceutical industry particularly in advancing treatments for diabetes

Custom Reviews

November 21, 2024

Crucial Intermediate for Synthesis Applications

Using (3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one was seamless in our research. It's essential for synthesizing vital inhibitors in antidiabetic drug development. Efficient and reliable!

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