4-(Tert-Butyl Dimethylsiloxy)Phenyl Boronic Acid

Catalog Number	ACM159191567
CAS Number	159191-56-7
Structure
Synonyms	4-(T-BUTYL DIMETHYLSILOXY) PHENYL BORONIC ACID;4-(TERT-BUTYL DIMETHYLSILOXY)PHENYL BORONIC ACID;4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID;4-(TERT-BUTYLDIMETHYLSILYOXY)PHENYLBORONIC ACID;AKOS BRN-0412;4-(TERT-BUTYLDIMETHYLSILYOXY)PHENYLBORON;4-(tert
IUPAC Name	[4-[tert-butyl(dimethyl)silyl]oxyphenyl]boronic acid
Molecular Weight	252.19 g/mol
Molecular Formula	C12H21BO3Si
Canonical SMILES	B(C1=CC=C(C=C1)O[Si](C)(C)C(C)(C)C)(O)O
InChI Key	NVHHEADQQACSCJ-UHFFFAOYSA-N
Boiling Point	321.4ºC at 760mmHg
Melting Point	194-198ºC(lit.)
Flash Point	148.2ºC
Purity	98%
Density	1.01g/cm³
Application	4-(Tert-Butyl Dimethylsiloxy)Phenyl Boronic Acid serves as a versatile reactant extensively utilized in various chemical syntheses It plays a critical role in asymmetric addition reactions involving β-substituted cyclic enones and facilitates hydroarylation and heterocyclization with phenylpropiolates This compound is integral to double Suzuki-Miyaura coupling reactions providing valuable intermediates for a range of applications Additionally it acts as a starting material in the creation of red electroluminescent polyfluorenes Its utility extends to the synthesis of biologically active molecules including phenylpyridone derivatives functioning as MCH1R antagonists as well as atromentin and its O-alkylated derivatives Furthermore it contributes to the development of inhibitors targeting gelatinases and MT1-MMP underscoring its importance in medicinal chemistry
Exact Mass	252.13500